Dr. Shreyans Kumar Jain

Associate Professor
Department/School/Unit Name
Department of Pharmaceutical Engineering and Technology
Phone No(s): 7165(5763), 8764331736
Email: sjain.phe@iitbhu.ac.in and shreyansrj@gmail
Area of Interest: Medicinal Chemistry of Natural Products and Metabolomics
2018- till date Assistant Professor
2016-2018 Postdoctoral, Georgetown University, Washington DC, USA
2015-2016 CSIR-RA, CSIR-Indian Institute of Integrative Medicine, Jammu
PhD, CSIR-Indian Institute of Integrative Medicine, Jammu
2010-2011 Project Assistant, CSIR-Indian Institute of Integrative Medicine, Jammu
2007-2010 Research Associate, Piramal Life Science. Mumbai
M.S. (Pharm), NIPER—Mohali.  
B. Pharmacy, Lachoo Memorial College of Science & Technology- Jodhpur

Drug Discovery: Medicinal Chemistry of Natural Products (Isolation, Characterization, Analysis and Synthesis)
Biomarker Discovery: LCMS based Metabolomics and Proteomics


  1. WO2014167580A1, US20160046611, EP2984078, C2909280, IN 2013DE01077, Vishwakarma, R.A.; Jain, S.K.; Bharate, S.B.; Dar, A.H.; Khajuria, A.; Samdarshi, M.; Bhola, S.K.; Qazi, A.K.; Hussain, A.; Sidiq, T.; Uma Shaanker, R.; Ravikanth, G.; Vasudeva, R.; Patel, M.K.; Ganeshaiah, K.N. New chromone alkaloid dysoline for the treatment of cancer and inflammatory disorders.


  1. WO2014170914A1, US20160052915, EP2986605, CA2908084, IN2013DE01142, Vishwakarma, R.A.; Bharate, S.B.; Bhushan, S.; Mondhe Dilip Manikrao; Jain, S.K.; Meena, S.; Guru, S.K.; Pathania, A.S.; Kumar, S. Behl Akanksha, Mintoo Mubashir Javed, Bharate Sonali Sandip and Joshi PrashantCyclin-dependent kinase inhibition by 5,7-dihydroxy-8-(3-hydroxy-1-methylpiperidin-4-yl)-2-methyl-4H-chromen-4-on analogs.


  1. WO2014188440A1, US20160122360, EP3004116, CA2913281, IN2013DE01565,Jain, S.K.; Sidiq, T.; Meena, S.; Khajuria, A.; Vishwakarma, R.A.; Bharate, S.B. Tetrahydro-2H-pyrano{3,2-C]-isochromene-6-ones and analogs for the treatment of inflammatory disorders.


  1. IN 201611002826. Bharate SB, Singh S, Singh GD, Jain SK, Kumar A, Singh B, Gupta AP, Anand R, Singh A, Kushwaha M, Gupta M, Sharma G, Sharma A, Vishwakarma RA. Standardized extract of Bergenia ciliata for the treatment of inflammatory disorders 


  1. Standardized Extract of Dysoxylum binectariferum for the treatment of inflammatory disorders (File in process)


  1. WO2019/003237 Al, PCT/IN20 18/050060, Mukherjee, Debaraj; goswami, anindya; Sharma, Deepak; Nayak, Debasis; Jain, Shreyans Kumar; Indolylkojyl Methane Analogues, Process of Preparation Thereof and Use As Inhibitor Of Cancer Cell Invasion And Metastasis

Book Chapters

1.    Tarkeshwar Dubey, Shreyans Kumar Jain, & Siva Hemalatha. Chapter Blumea lacera (Asteraceae), a Potential Herb of Medicinal Value in Modern Aspects. In: Singh Bikarma, Sharma Yash Pal, editors. From Ethnobotany to Ethnopharmacology: Exploiting Plants for Novel Drug Molecules. ed. New Delhi, India: New India Publishing Agency; 2021. p. 397-410.  Book Chapters

2.    Bharat Goel, Bharat Sahu, & Shreyans Kumar Jain*. Chapter Plant-Derived Drug Discovery: Introduction to Recent Approaches. In: Singh Bikarma, editor. Botanical Leads for Drug Discovery. ed. Singapore: Springer Singapore; 2020. p. 1-27. (doi: https://doi.org/10.1007/978-981-15-5917-4_1) Book Chapter

3.    Amrita K Cheema, Scott Grindrod, Xiaogang Zhong, Shreyans Jain, Smrithi S Menon, Khyati Y Mehta, Simeng Suy, Sean Collins, Yiwen Wang, & Olga Timofeeva. Chapter Discovery of Metabolic Biomarkers Predicting Radiation Therapy Late Effects in Prostate Cancer Patients. Human Cell Transformation. ed. Springer; 2019. p. 141-150. Book Chapters

4.    Shreyans Kumar Jain. Chapter Dysoxylum Binectariferum Hook.f., An Indian Medicinal Plant as a Source for Anti-Cancer Agents. In: Singh Bikarma, editor. Plants for Human Survival and Medicine. ed. New Delhi, India: New India Publishing Agency; 2019. p. 115-149. Book Chapters

5.    Nivedita Bhardwaj, Nancy Tripathi, Ram A. Vishwakarma, Shreyans K. Jain, Chapter Four - Advances in natural products driven drug discovery from medicinal plants for neuropathic pain, Editor(s): Karl-Heinz Altmann, Annual Reports in Medicinal Chemistry, Academic Press, Volume 61, 2023, Pages 133-162, https://doi.org/10.1016/bs.armc.2023.10.003.

Research Articles and Review

Year 2023

6.    Bhardwaj, N., A. Sharma, N. Tripathi, B. Goel, G. Ravikanth, S. Kumar Guru and S. K. Jain (2023). "New cycloartane triterpenoids from Dysoxylum malabaricum and their cytotoxic evaluation." Steroids 200: 109315. https://doi.org/10.1016/j.steroids.2023.109315

7.    Tripathi, N., N. Bhardwaj, S. Kumar and S. K. Jain "Phytochemical and pharmacological aspects of psoralen- A bioactive furanocoumarin from Psoralea corylifolia Linn." Chemistry & Biodiversity n/a(n/a): e202300867. https://doi.org/10.1002/cbdv.202300867

8.    Bhardwaj, N., N. Tripathi, S. Kumar and S. K. Jain (2023). "Synthesis of amides directly from carboxylic acids and hydrazines." Organic & Biomolecular Chemistry 21(37): 7572-7579. DOI https://doi.org/10.1039/D3OB01268A

9.    Goel, B., A. Naik, N. Tripathi, A. Khan, S. Bansal, S. Bansal, S. Kumar Guru and S. K. Jain (2023). "Synthesis, in vitro Cytotoxicity Evaluation, and Docking Studies of Gloriosine Derivatives as Potential Anticancer Agents." ChemistrySelect 8(32): e202301063. https://doi.org/10.1002/slct.202301063

10.    Goel, B.; Jaiswal, S.; Jain, S. K. Indole derivatives targeting colchicine binding site as potential anticancer agents. Archiv der Pharmazie, e2300210. DOI: https://doi.org/10.1002/ardp.202300210.

11.    Diksha Manhas, Shipra Bhatt, Garima Rai, Vinay Kumar, Sahil Bharti, Sumit Dhiman, Shreyans K. Jain, Deepak K. Sharma, Probir Kumar Ojha, Sumit G. Gandhi, Anindya Goswami, Utpal Nandi, Rottlerin renders a selective and highly potent CYP2C8 inhibition to impede EET formation for implication in cancer therapy, Chemico-Biological Interactions,2023, 110524 https://doi.org/10.1016/j.cbi.2023.110524 https://www.sciencedirect.com/science/article/pii/S0009279723001916

12.    Kumar, S.; Mishra, A.; Dwivedi, K. N.; Singh, N.; Kumar, A.; Bhartiya, S. K.; Krishnamoorthi, S.; Kumar, A.; Goel, B.; Jain, S. K. Evidence-Based Therapeutic Potential of Natural Seed Oil of Desert Date/Ingudi (Balanites aegyptiaca Linn. Delile) in Chronic Diabetic Wound. Proceedings of the National Academy of Sciences, India Section B: Biological Sciences 2023,  https://doi.org/10.1007/s40011-023-01487-y

13.    Tripathi, N., N. Bhardwaj, S. Kumar and S. K. Jain "A machine learning-based KNIME workflow to predict VEGFR-2 inhibitors." Chemical Biology & Drug Design  https://doi.org/10.1111/cbdd.14250

14.    Singh, V., K. S. Jain and V. Mishra (2023). "A Recent Update on SARS-CoV-2 Transmission and its Variants: Transmission, Pathogenic Mechanism, and Treatment." Coronaviruses 4(1): 3-15. DOI: 10.2174/2666796704666230102121225

15.    Kumar, S., N. Singh, A. Mittal, H. Kharkwal, S. K. Jain and B. Goel (2023). "The genus Leucas: A review on phytochemistry and pharmacological activities." Fitoterapia 167: 105492. https://doi.org/10.1016/j.fitote.2023.105492

Year 2022

16.    Goel, B.; Reddy, H.; Cholkar, A.; Kumar, S.; Guru, S. K.; Jain, S. K. Isolation of a new cytotoxic colchinoid from Gloriosa superba roots. Natural Product Research 2022, DOI:10.1080/14786419.2022.2158464

17.    Goel, B.; Jain, S. K. Natural products as a source of cytotoxic warheads in antibody-drug conjugates. Natural Product Research 2022, DOI:10.1080/14786419.2022.2138872
18.    Goel, B.; Dey, B.; Chatterjee, E.; Tripathi, N.; Bhardwaj, N.; Kumar, S.; Guru, S. K.; Jain, S. K., Antiproliferative Potential of Gloriosine: A Lead for Anticancer Drug Development. ACS Omega 2022. https://doi.org/10.1021/acsomega.2c02688 (IF:4.132) 

19.    Kushwaha, M.; Qayum, A.; Sharma, N.; Abrol, V.; Choudhary, P.; Murtaza, M.; Singh, S. K.; Vishwakarma, R. A.; Goutam, U.; Jain, S. K.; Jaglan, S., LC–PDA–MS/MS-Based Dereplication Guided Isolation of a New Optical Isomer of 19,20-Epoxycytochalasin-N and Its Cytotoxic Activity. ACS Omega 2022. https://doi.org/10.1021/acsomega.2c03037  (Co-corresponding, IF:4.132)

20.    Tripathi, N.; Goel, B.; Bhardwaj, N.; Vishwakarma, R. A.; Jain, S. K., Exploring the Potential of Chemical Inhibitors for Targeting Post-translational Glycosylation of Coronavirus (SARS-CoV-2). ACS Omega 2022.   https://doi.org/10.1021/acsomega.2c02345 (corresponding , INVITED REVIEW) IF: 4.132

21.    Shreya, S.; Jain, S. K.; Guru, K. S.; Sahu, N. A., Anti-cancer potential of Pleurotus mushroom: Detailed insight on the potential bioactive molecules, Invitro-Invivo studies, and formulation. Letters in Drug Design & Discovery, 2022. 19: p. 1-1. DOI: 10.2174/1570180819666220518100010 (IF 1.02)

22.    Ramakrishna, K., S.K. Jain, and S. Krishnamurthy, Pharmacokinetic and Pharmacodynamic Properties of Indole-3-carbinol in Experimental Focal Ischemic Injury. European Journal of Drug Metabolism and Pharmacokinetics, 2022. 47(4): p. 593-605. https://doi.org/10.1007/s13318-022-00771-y (IF 2.46)

23.    Jayesh Tiwari, Nancy Tripathi, Ravi Shanker Srivastava, Sujeet Kumar, Sanjay Singh, Shreyans Jain, Arun Khattri, Low expression of TMPRSS2–a SARS-CoV-2 internalization protease–associates with basal subtype of head and neck squamous cell carcinoma, Translational Oncology, 22, 2022, 101458, https://doi.org/10.1016/j.tranon.2022.101458. (IF 4.243)

24.    Goel B, Tiwari AK, Pandey RK, Singh AP, Kumar S, Sinha A, Jain SK, Khattri A. 2022. Therapeutic approaches for the treatment of head and neck squamous cell carcinoma–An update on clinical trials. Translational Oncology. 2022/07/01/;21:101426. https://doi.org/10.1016/j.tranon.2022.101426  (IF 4.243)

25.    Goel B, Tripathi N, Bhardwaj N, Kumar A, Jain SK. 2022. Iodine-mediated one-step synthesis of ipomone from gibberellic acid. Natural Product Research.1-8. https://doi.org/10.1080/14786419.2022.2065487 (IF 2.861)

26.    Nalli, Y. K., S. K. Guru, P. Jain, V. Mishra and S. K. Jain (2022). "Bioassay-Guided Fractionation and Dereplication Studies of Sesame oil: Isolation of 8-Acetoxypinoresinol as an Anti-Proliferative Metabolite and Prediction of Target." Proceedings of the National Academy of Sciences, India Section B: Biological Sciences. https://doi.org/10.1007/s40011-021-01308-0 (IF: 0.96)

27.    Prasad J, Das S, Maurya A, Jain SK, Dwivedy AK. (2022) Synthesis, characterization and in situ bioefficacy evaluation of Cymbopogon nardus essential oil impregnated chitosan nanoemulsion against fungal infestation and aflatoxin B1 contamination in food system. International Journal of Biological Macromolecules. https://doi.org/10.1016/j.ijbiomac.2022.02.060  (IF 6.953)

28.    Sahu, B., N. Bhardwaj, E. Chatterjee, B. Dey, N. Tripathi, B. Goel, M. Kushwaha, B. Kumar, B. Singh, S. K. Guru and S. K. Jain (2022). "LCMS-DNP based dereplication of Araucaria cunninghamii Mudie gum-resin: identification of new cytotoxic labdane diterpene." Natural Product Research: 1-8. https://doi.org/10.1080/14786419.2021.2024530 (IF 2.861)

Year 2021

29.    Rajagopal, M. U., S. Bansal, P. Kaur, S. K. Jain, T. Altadil, C. P. Hinzman, Y. Li, J. Moulton, B. Singh, S. Bansal, S. K. Chauthe, R. Singh, P. P. Banerjee, M. Mapstone, M. S. Fiandaca, H. J. Federoff, K. Unger, J. P. Smith and A. K. Cheema (2021). "TGFβ Drives Metabolic Perturbations during Epithelial Mesenchymal Transition in Pancreatic Cancer: TGFβ Induced EMT in PDAC." Cancers 13(24). https://doi.org/10.3390/cancers13246204 (IF 6.639)

30.    Bhardwaj N, Goel B, Tripathi N, Sahu B, Jain SK. 2021. A Comprehensive Review on Chemistry and Pharmacology of Marine Bioactives as Antimetastatic Agents. European Journal of Medicinal Chemistry Reports. 2021/12/07/:100023. (Review Article)

31.    Manhas D, Gour A, Bhardwaj N, Sharma DK, Sharma K, Vij B, Jain SK, Singh G, Nandi U. 2021. Pharmacokinetic Assessment of Rottlerin from Mallotus philippensis Using a Highly Sensitive Liquid Chromatography–Tandem Mass Spectrometry-Based Bioanalytical Method. ACS Omega. 2021/12/07;6:32637-32646. (IF 3.512)

32.    N. Bhardwaj, A. K. Singh, N. Tripathi, B. Goel, A. Indra and Shreyans K. Jain. "Ni-NiO Heterojunction: A Versatile Nanocatalyst for the Regioselective Halogenation and Oxidative Esterification of Aromatics. New Journal of Chemistry. 2021 Accepted: https://doi.org/10.1039/D1NJ02777H (IF 3.288)

33.    Bharat Goel, Essha Chatterjee, Biswajit Dey, Nancy Tripathi, Nivedita Bhardwaj, Arun Khattri, Santosh Kumar Guru, and Shreyans K. Jain* Identification and Evaluation of Apoptosis-Inducing Activity of Ipomone from Ipomoea nil: A Novel, Unusual Bicyclo-[3.2.1] Octanone Containing Gibberic Acid Diterpenoid."ACS Omega 2021, 6, 12, 8253–8260 https://doi.org/10.1021/acsomega.0c06304) (IF 3.512)

34.    Manoj Kushwaha, Arem Qayum, Shreyans K. Jain, Jasvinder singh, Amit Srivastava, Shubham Srivastava, Nisha Sharma, Vidushi Abrol, Ruchi Malik, Shashank Singh, Ram A. Vishwakarma, Sandeep  Jaglan, The Tandem MS-based metabolite profiling of 19,20-epoxycytochalasin C, reveals the importance of hydroxy group at the C-7 position for biological activity" ACS Omega 2021, 6, 5, 3717–3726, https://doi.org/10.1021/acsomega.0c05307) (IF 3.512)

35.    Bharat Goel, Nancy Tripathi, Debaraj Mukherjee & Shreyans K. Jain*, Glycorandomization: A promising diversification strategy for the drug development. European Journal of Medicinal Chemistry, 2021: 213, 113156 https://doi.org/10.1016/j.ejmech.2021.113156) (I.F- 5.572) Review Article

36.    Nivedita Bhardwaj, Nancy Tripathi, Bharat Goel & Shreyans K. Jain*, Anticancer Activity of Diosgenin and its Semi-synthetic Derivatives: Role in Autophagy Mediated Cell Death and Induction of Apoptosis. Mini-Reviews in Medicinal Chemistry, 2020. (Accepted, https://doi.org/10.2174/1389557521666210105111224) (I.F-2.73), Review Article

Year 2020

37.    Bharat Goel, Nivedita Bhardwaj, Nancy Tripathi, & Shreyans K. Jain*, Drug discovery of small molecules for the treatment of COVID-19: A review on clinical studies. Mini-Reviews in Medicinal Chemistry, 2020. (doi: https://doi.org/10.2174/1389557521666201228145755) (I.F-2.73), Review Article

38.    Nancy Tripathi, Bharat Goel, Nivedita Bhardwaj, Bharat Sahu, Hemant Kumar, & Shreyans K. Jain*, Virtual screening and molecular simulation study of natural products database for lead identification of novel coronavirus main protease inhibitors. Journal of Biomolecular Structure and Dynamics, 2020: 1-13. (doi: https://doi.org/10.1080/07391102.2020.1848630) (I.F-3.310) 

39.    Bharat Goel, Ved Vyas, Nancy Tripathi, Ajit Kumar Singh, Prashanth W. Menezes, Arindam Indra, & Shreyans K. Jain*, Amidation of Aldehydes with Amines under Mild Conditions Using Metal-Organic Framework Derived NiO@Ni Mott-Schottky Catalyst. ChemCatChem, 12, 2020: 5743-5749. (doi: https://doi.org/10.1002/cctc.202001041) (I.F-4.853)

40.    Bharat Goel, Nancy Tripathi, Nivedita Bhardwaj, Bharat Sahu, & Shreyans K. Jain*, Therapeutic potential of genus Pongamia and Derris: Phytochemical and bioactivity. Mini-Reviews in Medicinal Chemistry, 2020. (doi: https://doi.org/10.2174/1389557520999201124211846) (I.F-2.73), Review Article

41.    Bharat Goel, Nancy Tripathi, Nivedita Bhardwaj, & Shreyans K. Jain*, Small Molecule CDK Inhibitors for the Therapeutic Management of Cancer. Current Topics in Medicinal Chemistry, 20, 2020: 1535-1563. (doi: https://doi.org/10.2174/1568026620666200516152756) (I.F-3.218), Review Article

42.    Bharat Goel, Anuradha Sharma, Nancy Tripathi, Nivedita Bhardwaj, Bharat Sahu, Gurcharan Kaur, Bikarma Singh, & Shreyans K. Jain*, In-vitro antitumor activity of compounds from Glycyrrhiza glabra against C6 glioma cancer cells: identification of natural lead for further evaluation. Natural Product Research, 2020. (doi: https://doi.org/10.1080/14786419.2020.1786830) (I.F-2.158)

43.    Manoj Kushwaha, Bharat Goel, Sundeep Jaglan, & Shreyans K. Jain*, LC-MS/MS profile of an active pharmaceutical ingredient and its impurities in commercial preparation. Journal of Liquid Chromatography & Related Technologies, 43, 2020: 131-137. (doi: https://doi.org/10.1080/10826076.2019.1680561) (I.F-0.992)

44.    Priti Jain, Shreyans K. Jain, & Munendra Jain, Harnessing Drug Repurposing for Exploration of New Diseases: An Insight to Strategies and Case Studies. Current Molecular Medicine, 2020. (doi: https://doi.org/10.2174/1566524020666200619125404) (I.F-1.6), Review Article

Year 2019

45.    Rohit Singh, Kapil Mandrah, Ankita Asati, Devendra K. Patel, Bharat Goel, Ram A. Vishwakarma, Somendu K. Roy, & Shreyans K. Jain*, Transformation of Santonin to a Naproxen Analogue with Anti-Inflammatory Activity. Journal of Natural Products, 82, 2019: 1710-1713. (doi: https://doi.org/10.1021/acs.jnatprod.8b00318) (I.F-3.779) 

46.    P. Rajani, H. Aiswarya, M. M. Vasanthakumari, Shreyans K. Jain, Sandip B. Bharate, C. Rajasekaran, G. Ravikanth, & R. Uma Shaanker, Inhibition of the collar rot fungus, Sclerotium rolfsii Sacc. by an endophytic fungus Alternaria sp.: implications for biocontrol. Plant Physiology Reports, 24, 2019: 521-532. (doi: https://doi.org/10.1007/s40502-019-00484-6) (I.F-0.217)

47.    Evan L. Pannkuk, Evagelia C. Laiakis, Kirandeep Gill, Shreyans K. Jain, Khyati Y. Mehta, Denise Nishita, Kim Bujold, James Bakke, Janet Gahagen, Simon Authier, Polly Chang, & Albert J. Fornace, Liquid Chromatography–Mass Spectrometry-Based Metabolomics of Nonhuman Primates after 4 Gy Total Body Radiation Exposure: Global Effects and Targeted Panels. Journal of Proteome Research, 18, 2019: 2260-2269. (doi: https://doi.org/10.1021/acs.jproteome.9b00101) (I.F-4.074)

48.    Asma Derf, Shilpa A. Verekar, Shreyans K. Jain, Sunil K. Deshmukh, Sandip B. Bharate, & Bhabatosh Chaudhuri, Radicicol rescues yeast cell death triggered by expression of human α-synuclein and its A53T mutant, but not by human βA4 peptide and proapoptotic protein bax. Bioorganic Chemistry, 85, 2019: 152-158. (doi: https://doi.org/10.1016/j.bioorg.2018.12.033) (I.F-4.831)

49.    Mohd Ishaq Dar, Priya Mahajan, Suraya Jan, Shreyans K. Jain, Harshita Tiwari, Jagjeet Sandey, Sandip Bharate, Amit Nargotra, & Sajad Hussain Syed, Rottlerin is a pan phosphodiesterase inhibitor and can induce neurodifferentiation in IMR-32 human neuroblastoma cells. European Journal of Pharmacology, 857, 2019: 172448. (doi: https://doi.org/10.1016/j.ejphar.2019.172448) (I.F-3.263)

Year 2018

50.    Keith Unger, Khyati Y. Mehta, Prabhjit Kaur, Yiwen Wang, Smrithi S. Menon, Shreyans K. Jain, Rose A. Moonjelly, Shubhankar Suman, Kamal Datta, Rajbir Singh, Paul Fogel, & Amrita K. Cheema, Metabolomics based predictive classifier for early detection of pancreatic ductal adenocarcinoma. Oncotarget, 9, 2018: 23078-23090. (doi: https://doi.org/10.18632/oncotarget.25212) (I.F-5.168) 

51.    N. Sharma, M. Kushwaha, D. Arora, Shreyans Jain, V. Singamaneni, S. Sharma, R. Shankar, S. Bhushan, P. Gupta, & S. Jaglan, New cytochalasin from Rosellinia sanctae-cruciana, an endophytic fungus of Albizia lebbeck. Journal of Applied Microbiology, 125, 2018: 111-120. (doi: https://doi.org/10.1111/jam.13764) (I.F-3.066)

52.    Manoj Kushwaha, Shreyans K. Jain, Nisha Sharma, Vidushi Abrol, Sundeep Jaglan, & Ram A. Vishwakarma, Establishment of LCMS Based Platform for Discovery of Quorum Sensing Inhibitors: Signal Detection in Pseudomonas aeruginosa PAO1. ACS Chemical Biology, 13, 2018: 657-665. (doi: https://doi.org/10.1021/acschembio.7b00875) (I.F-4.434) 

53.    Amrita Cheema, Scott Grindrod, Simeng Suy, Xiaogang Zhong, Shreyans Jain, Khyati Mehta, Gaurav Bandi, Keith Kowalczyk, John Lynch, Sean Collins, & Anatoly Dritschilo, MP35-11 METABOLIC BIOMARKERS ARE PREDICTIVE OF RESPONSE TO RADIATION THERAPY IN PROSTATE CANCER PATIENTS. Journal of Urology, 199, 2018: e451-e451. (doi: https://doi.org/10.1016/j.juro.2018.02.1124) (I.F-5.92)

54.    Sandip B. Bharate, Vikas Kumar, Shreyans K. Jain, Mubashir J. Mintoo, Santosh K. Guru, Vijay K. Nuthakki, Mohit Sharma, Sonali S. Bharate, Sumit G. Gandhi, Dilip M. Mondhe, Shashi Bhushan, & Ram A. Vishwakarma, Discovery and Preclinical Development of IIIM-290, an Orally Active Potent Cyclin-Dependent Kinase Inhibitor. Journal of Medicinal Chemistry, 61, 2018: 1664-1687. (doi: https://doi.org/10.1021/acs.jmedchem.7b01765) (I.F-6.2): (Equal contribution to first four anthours)

Year 2017 and Before

55.    Naveen Shivavedi, & Shreyans K Jain*, Review on the discovery of rohitukine-inspired CDK inhibitors. The Pharmstudent, 28, 2017: 50-58.

56.    Rajni Sharma, Linda Gatchie, Ibidapo S. Williams, Shreyans K. Jain, Ram A. Vishwakarma, Bhabatosh Chaudhuri, & Sandip B. Bharate, Glycyrrhiza glabra extract and quercetin reverses cisplatin resistance in triple-negative MDA-MB-468 breast cancer cells via inhibition of cytochrome P450 1B1 enzyme. Bioorganic & Medicinal Chemistry Letters, 27, 2017: 5400-5403. (doi: https://doi.org/10.1016/j.bmcl.2017.11.013) (I.F-5.1)

57.    Masroor Qadri, Yedukondalu Nalli, Shreyans K. Jain, Asha Chaubey, Asif Ali, Gary A. Strobel, Ram A. Vishwakarma, & Syed Riyaz-Ul-Hassan, An Insight into the Secondary Metabolism of Muscodor yucatanensis: Small-Molecule Epigenetic Modifiers Induce Expression of Secondary Metabolism-Related Genes and Production of New Metabolites in the Endophyte. Microbial Ecology, 73, 2017: 954-965. (doi: https://doi.org/10.1007/s40502-019-00484-6) (I.F-3.356)

58.    Saima Khan, Pankaj Pandotra, Malik Muzafar Manzoor, Manoj Kushwaha, Rajni Sharma, Shreyansh Jain, Ashok Ahuja, Vishal Amancha, Sashi Bhushan, Santosh Kumar Guru, Ajai Prakash Gupta, Ram Vishwakarma, & Suphla Gupta, Terpenoid and flavonoid spectrum of in vitro cultures of Glycyrrhiza glabra revealed high chemical heterogeneity: platform to understand biosynthesis. Plant Cell, Tissue and Organ Culture (PCTOC), 124, 2016: 507-516. (doi: https://doi.org/10.1007/s11240-015-0910-4) (I.F-2.196)

59.    Vikas Kumar, Santosh K. Guru, Shreyans K. Jain, Prashant Joshi, Sumit G. Gandhi, Sandip B. Bharate, Shashi Bhushan, Sonali S. Bharate, & Ram A. Vishwakarma, A chromatography-free isolation of rohitukine from leaves of Dysoxylum binectariferum: Evaluation for in vitro cytotoxicity, Cdk inhibition and physicochemical properties. Bioorganic & Medicinal Chemistry Letters, 26, 2016: 3457-3463. (doi: https://doi.org/10.1016/j.bmcl.2016.06.046) (I.F-5.1)

60.    Samdarshi Meena, Rohit Singh, Ram A. Vishwakarma, Mushtaq A. Aga, & Shreyans K. Jain*, SeO2 mediated efficient synthesis of amides and α-ketoamides of secondary amines with wide substrate scope. Tetrahedron Letters, 57, 2016: 3715-3717. (doi: https://doi.org/10.1016/j.tetlet.2016.06.129) (I.F-2.275)

61.    Rajni Sharma, Santosh K. Guru, Shreyans K. Jain, Anup Singh Pathania, Ram A. Vishwakarma, Shashi Bhushan, & Sandip B. Bharate, 3-(2,6-Dichloro-benzyloxy)-11-oxo-olean-12-ene-29-oic acid, a semisynthetic derivative of glycyrrhetic acid: synthesis, antiproliferative, apoptotic and anti-angiogenesis activity. MedChemComm, 6, 2015: 564-575. (doi: https://doi.org/10.1039/C4MD00344F) (I.F-2.394)

62.    Baljinder Singh, Shreyans K. Jain, Sandip B. Bharate, Manoj Kushwaha, Ajai Prakash Gupta, & Ram A. Vishwakarma, Simultaneous Quantification of Five Bioactive Flavonoids in High Altitude Plant Actinocarya tibetica by LC-ESI-MS/MS. Journal of AOAC INTERNATIONAL, 98, 2015: 907-912. (doi: https://doi.org/10.5740/jaoacint.14-270) (I.F-1.510)

63.    Shreyans K. Jain, K. A. Aravinda Kumar, Sandip B. Bharate, & Ram A. Vishwakarma, Facile access to amides and hydroxamic acids directly from nitroarenes. Organic & Biomolecular Chemistry, 12, 2014: 6465-6469. (doi: https://doi.org/10.1039/C4OB01155D) (I.F-3.41)

64.    Shreyans K. Jain, Samdarshi Meena, Ajai P. Gupta, Manoj Kushwaha, R. Uma Shaanker, Sundeep Jaglan, Sandip B. Bharate, & Ram A. Vishwakarma, Dysoxylum binectariferum bark as a new source of anticancer drug camptothecin: Bioactivity-guided isolation and LCMS-based quantification. Bioorganic & Medicinal Chemistry Letters, 24, 2014: 3146-3149. (doi: https://doi.org/10.1016/j.bmcl.2014.05.001) (I.F-2.572)

65.    Shreyans K. Jain, Surjeet Singh, Anamika Khajuria, Santosh K. Guru, Prashant Joshi, Samdarshi Meena, Janhavi R. Nadkarni, Amarinder Singh, Sonali S. Bharate, Shashi Bhushan, Sandip B. Bharate, & Ram A. Vishwakarma, Pyrano-isochromanones as IL-6 Inhibitors: Synthesis, in Vitro and in Vivo Antiarthritic Activity. Journal of Medicinal Chemistry, 57, 2014: 7085-7097. (doi: https://doi.org/10.1021/jm500901e) (I.F-6.205)

66.    Prashant Joshi, Samsher Singh, Abubakar Wani, Sadhana Sharma, Shreyans K. Jain, Baljinder Singh, Bishan D. Gupta, Naresh K. Satti, Surrinder Koul, Inshad A. Khan, Ajay Kumar, Sandip B. Bharate, & Ram A. Vishwakarma, Osthol and curcumin as inhibitors of human Pgp and multidrug efflux pumps of Staphylococcus aureus: reversing the resistance against frontline antibacterial drugs. MedChemComm, 5, 2014: 1540-1547. (doi: https://doi.org/10.1039/C4MD00196F) (I.F-2.394)

67.    Jaideep B. Bharate, Santosh K. Guru, Shreyans K. Jain, Samdarshi Meena, Parvinder Pal Singh, Shashi Bhushan, Baldev Singh, Sandip B. Bharate, & Ram A. Vishwakarma, Cu–Mn spinel oxide catalyzed synthesis of imidazo[1,2-a]pyridines through domino three-component coupling and 5-exo-dig cyclization in water. RSC Advances, 3, 2013: 20869-20876. (doi: https://doi.org/10.1039/C3RA42046A) (I.F-3.119)

68.    Sandip B. Bharate, Baljinder Singh, Jaideep B. Bharate, Shreyans K. Jain, Samdarshi Meena, & Ram A. Vishwakarma, QSAR and pharmacophore modeling of N-acetyl-2-aminobenzothiazole class of phosphoinositide-3-kinase-α inhibitors. Medicinal Chemistry Research, 22, 2013: 890-899. (doi: https://doi.org/10.1007/s00044-012-0081-3) (I.F-1.783)

69.    Shreyans K. Jain, Samdarshi Meena, Asif K. Qazi, Aashiq Hussain, Sunil K. Bhola, Rajendra Kshirsagar, Koteppa Pari, Anamika Khajuria, Abid Hamid, R. Uma Shaanker, Sandip B. Bharate, & Ram A. Vishwakarma, Isolation and biological evaluation of chromone alkaloid dysoline, a new regioisomer of rohitukine from Dysoxylum binectariferum. Tetrahedron Letters, 54, 2013: 7140-7143. (doi: https://doi.org/10.1016/j.tetlet.2013.10.096) (I.F-2.275)

70.    Shreyans K. Jain, Anup S. Pathania, Samdarshi Meena, Rajni Sharma, Ashok Sharma, Baljinder Singh, Bishan D. Gupta, Shashi Bhushan, Sandip B. Bharate, & Ram A. Vishwakarma, Semisynthesis of Mallotus B from Rottlerin: Evaluation of Cytotoxicity and Apoptosis-Inducing Activity. Journal of Natural Products, 76, 2013: 1724-1730. (doi: https://doi.org/10.1021/np400433g) (I.F-3.779)

71.    Shreyans K. Jain, Anup S. Pathania, Rajinder Parshad, Chandji Raina, Asif Ali, Ajai P. Gupta, Manoj Kushwaha, Subrayashastry Aravinda, Shashi Bhushan, Sandip B. Bharate, & Ram A. Vishwakarma, Chrysomycins A–C, antileukemic naphthocoumarins from Streptomyces sporoverrucosus. RSC Advances, 3, 2013: 21046-21053. (doi: https://doi.org/10.1039/C3RA42884B) (I.F-3.119)

72.    P. Mishra, Shilpa Verekar, Asha Kulkarni-Almeida, Somendu Roy, Shreyans Jain, Arun Balakrishnan, R. Vishwakarma, & Sunil Deshmukh, Anti-inflammatory and anti-diabetic naphtha quinones from an endophytic fungus Dendryphion nanum (Nees) S. Hughes. Indian Journal of Chemistry Section B, 52B, 2013: 565-567. (I.F-0.388)

73.    Baljinder Singh, Santosh K. Guru, Smit Kour, Shreyans K. Jain, Rajni Sharma, Parduman R. Sharma, Shashank K. Singh, Shashi Bhushan, Sandip B. Bharate, & Ram A. Vishwakarma, Synthesis, antiproliferative and apoptosis-inducing activity of thiazolo[5,4-d]pyrimidines. European Journal of Medicinal Chemistry, 70, 2013: 864-874. (doi: https://doi.org/10.1016/j.ejmech.2013.10.039) (I.F-5.572)

74.    Baljinder Singh, Tabasum Sidiq, Prashant Joshi, Shreyans K. Jain, Yogesh Lawaniya, Surinder Kichlu, Anamika Khajuria, Ram A. Vishwakarma, & Sandip B. Bharate, Anti-inflammatory and immunomodulatory flavones from Actinocarya tibetica Benth. Natural Product Research, 27, 2013: 2227-2230. (doi: https://doi.org/10.1080/14786419.2013.805334) (I.F-2.158)

75.    Shreyans Kumar Jain, Sandip B. Bharate, & Ram A. Vishwakarma, Cyclin-Dependent Kinase Inhibition by Flavoalkaloids. Mini-Reviews in Medicinal Chemistry, 12, 2012: 632-649. (doi: http://dx.doi.org/10.2174/138955712800626683) (I.F-2.73)

76.    Shreyans K. Jain, Samdarshi Meena, Baljinder Singh, Jaideep B. Bharate, Prashant Joshi, Varun P. Singh, Ram A. Vishwakarma, & Sandip B. Bharate, KF/alumina catalyzed regioselective benzylation and benzoylation using solvent-free grind-stone chemistry. RSC Advances, 2, 2012: 8929-8933. (doi: https://doi.org/10.1021/np400433g) (I.F-3.119)

77.    Ramesh Mudududdla, Shreyans K. Jain, Jaideep B. Bharate, Ajai P. Gupta, Baldev Singh, Ram A. Vishwakarma, & Sandip B. Bharate, ortho-Amidoalkylation of Phenols via Tandem One-Pot Approach Involving Oxazine Intermediate. The Journal of Organic Chemistry, 77, 2012: 8821-8827. (doi: https://doi.org/10.1021/jo3017132) (I.F-4.335)

78.    Inder Pal Singh, Shreyans Kumar Jain, Amandeep Kaur, Sukhvinder Singh, Rajender Kumar, Prabha Garg, Shyam Sundar Sharma, & Sunil Kumar Arora, Synthesis and Antileishmanial activity of Piperoyl-Amino Acid Conjugates. European Journal of Medicinal Chemistry, 45, 2010: 3439-3445. (doi: https://doi.org/10.1016/j.ejmech.2010.04.033) (I.F-5.572)

      1.    Qualified GATE 2003-2004: AIR -102 (98.94 pecentile). 
2.    Qualified GATE 2003AIR -108 (97.94 pecentile). 
3.    Qualified NIPER entrance for admission in MS (Pharm).
4.    Award CSIR SRF 2012 
5.    Award CSIR Research Associateship 2014-2015
6.    Best Patent award on CSIR Foundation day Sept 26, 2014
7.    Best Research Paper award on CSIR Foundation day Sep 26, 2015
8.    Award for outstanding contribution to compound library on CSIR Foundation day Sep 26, 2015
9.    Dr PC Vyas Memorial Award at Rajasthan Science Congress 8 (2021) 


1.    Seed Money IIT BHU 10 Lakh (2018)

2.    Industrial consultancy project: 18 Lac (1 Yr) (2019-20)

3.    DST Supported grant: Approx Rs.64 Lac (3 Yr) (2022)

4.    SERB- CRG, approx.  31 lac (3 Yr) (2023)