Dr. Abha Mishra
Presently, Dr. Abha Mishra is working as Professor at the School of Biochemical Engineering, Indian Institute of Technology (BHU), Varanasi, with over two decades of academic and research experience in the fields of Fermentation Technology, Drug Discovery and Development, Drug Delivery Techniques, and Intellectual Property Rights. She earned her Ph.D. in Biochemical Engineering from IIT (BHU) in 2001, after completing her M.Tech. in Biochemical Engineering with First Rank distinction. Her academic journey reflects a strong multidisciplinary foundation, beginning with a B.Sc. in Chemistry (Hons.) with Botany and Zoology from Banaras Hindu University, followed by an M.Sc. in Biochemistry. She further expanded her expertise by obtaining a Postgraduate Diploma in Intellectual Property Rights from IGNOU.
At IIT (BHU), Prof. Mishra has significantly contributed to teaching, mentoring, and research through her roles as Assistant Professor (2003–2016), Associate Professor (2016–2024), and currently as Professor (since 2024) and Associate Dean R&D, IIT-BHU. Prior to joining IIT (BHU), she served as a Lecturer at Jaypee University of Information Technology, Solan.
Education Qualification:
|
S.no. |
Degree |
Univ/Inst |
Year |
Branch/Stream |
|
1. |
B.Sc. |
Banaras Hindu University |
1993 |
Chemistry (Hons), Botany, Zoology |
|
2. |
M.Sc. |
Biochemistry |
1995 |
Biochemistry |
|
3. |
M.Tech. |
Biochemical Engineering |
1997 |
Biochemical Engineering |
|
4. |
Ph.D. |
Biochemical Engineering |
2001 |
Biochemical Engineering |
|
5. |
PG diploma |
IGNOU |
2011 |
Intellectual Property Rights |
Employment Details:
|
S.no |
Designation |
Organization/Place |
Period From-To |
Job Responsibility |
|
1. |
Professor |
IIT(BHU) |
5 Jan 2024 -still continuing |
Teaching and Research |
|
2. |
Associate Professor |
IIT(BHU) |
1 Sept 2016-4 Jan 2024 |
Teaching and Research |
|
3. |
Assistant Professor |
IIT(BHU) |
8 Aug 2003-31 Aug 2016 |
Teaching and Research |
|
4. |
Lecturer |
Jaypee University of Information Technol. Solan HP |
8 Aug 2002-7 Aug 2003 |
Teaching and Research |
List of Publications:
2025
119. Shukla, Alok, Arpit Sharma, Shivani Gupta, Shruti Raut, Abha Mishra, Siva Hemalatha, and Amit Singh. "Structure-guided discovery of a novel BTK inhibitor inducing apoptosis and G1 phase arrest in tumor cells." Molecular Diversity (2025): 1-24. https://doi.org/10.1007/s11030-025-11334-z
118. Raut, Shruti S., Arpit Sharma, and Abha Mishra. "Nano‐Bioremediation via Biochar, Zeolite Nanocomposites for Water Quality Enhancement: A Review." Water Environment Research 97, no. 7 (2025): e70151, https://doi.org/10.1002/wer.70151
117. Arpit Sharma, Shruti S. Raut, Alok Shukla, Shivani Gupta, Abha Mishra, Amit Singh, From tissue architecture to clinical insights: Spatial transcriptomics in solid tumor studies, Seminars in Oncology, Volume 52, Issue 5, 2025,152389, ISSN 0093-7754, https://doi.org/10.1016/j.seminoncol.2025.152389
116. Shruti Sharadrao Raut, Arpit sharma, Abha Mishra, Lignocellulosic biomass-driven biohydrogen production: Innovations, challenges, and future prospects for a sustainable green hydrogen economy, International Journal of Hydrogen Energy, Volume 132, 2025, Pages 51-74, ISSN 0360-3199, https://doi.org/10.1016/j.ijhydene.2025.04.268
115. Shruti S. Raut, Arpit Sharma, Ankit Keshariya, Vansh Agarwal, Rohit Kumar, Abha Mishra, Artificial intelligence-driven optimization of biohydrogen production: ANN-GA, RSM, and python synergy for novel Alcaligenes ammonioxydans utilizing sugarcane bagasse, Fuel, Volume 399, 2025, 135647, ISSN 0016-2361, https://doi.org/10.1016/j.fuel.2025.135647
114. Aditi Bhatnagar, Abhay Dev Tripathi, Sonali Kumari, Abha Mishra, Cadmium sulfide nanoparticles (CdSNPs) modulate key oncogenic pathways in PA1 ovarian cancer cells: Insights from transcriptomic analysis, Toxicology in Vitro, Volume 107, 2025, 106079, ISSN 0887-2333, https://doi.org/10.1016/j.tiv.2025.106079
113. Shukla, A., Sharma, A., Gupta, S., Mishra, A. et al. Antitumor potential of ivermectin against T-cell lymphoma-bearing hosts. Med Oncol 42, 169 (2025). https://doi.org/10.1007/s12032-025-02726-0
112. Gupta, S., Sharma, A., Shukla, A., Mishra, A. et al. From development to clinical success: the journey of established and next-generation BTK inhibitors. Invest New Drugs 43, 377–393 (2025). https://doi.org/10.1007/s10637-025-01513-y
2024
111. Shukla P, Srivastava P, Mishra A (2024) Routes of Exposure (Inhalation, Ingestion, Dermal Contact) of Heavy Metals and Their Implications for Human Health. In: Heavy Metal Contamination in the Environment. CRC Press
110. Raut, S.S., sharma, A., Mishra, P.K. et al. Isolation and characterization of novel bacterial strain from sewage sludge and exploring its potential for hydrogen production. Arch Microbiol 207, 10 (2025). https://doi.org/10.1007/s00203-024-04211-0
109. Singh, V., Kumar, A., Mishra, V., & Rai, S.N. (Eds.). (2024). Heavy Metal Contamination in the Environment: Health Impacts and Potential Remediation Approaches (1st ed.). CRC Press. https://doi.org/10.1201/9781032685793
108. Sharma, A., Raut, S.S., Shukla, A. Mishra, A. DDX3X dynamics, glioblastoma's genetic landscape, therapeutic advances, and autophagic interplay. Med Oncol 41, 258 (2024). https://doi.org/10.1007/s12032-024-02525-z
107. A. D. Tripathi, Y. Labh, S. Katiyar, A. K. Singh, V. K. Chaturvedi, and A. Mishra, “Folate-Mediated Targeting and Controlled Release: PLGA-Encapsulated Mesoporous Silica Nanoparticles Delivering Capecitabine to Pancreatic Tumor,” ACS Appl. Bio Mater., Mar. 2024, doi: 10.1021/acsabm.4c00019.
106. Tripathi, A.D., Labh, Y., Katiyar, S. et al. Advancements in Nano-Mediated Biosensors: Targeting Cancer Exosome Detection. J Clust Sci 35, 2195–2212 (2024). https://doi.org/10.1007/s10876-024-02676-z
105. A. D. Tripathi, V. K. Pandey, S. Katiyar, and A. Mishra, “The Emerging Role of Biosensors in the Identification, Characterization, and use of Natural Bioactive Compounds,” in Recent Advances in Biosensor Technology: Volume 2, Bentham Science Publishers, 2023, pp. 1–15. Accessed: Dec. 29, 2024. [Online]. Available:DOI: https://doi.org/10.2174/97898151237391230101https://www.benthamdirect.com/content/books/9789815136418.chap1
104. S. Katiyar, A. D. Tripathi, R. K. Singh, A. Kumar Chaurasia, P. K. Srivastava, and A. Mishra, “Graphene-silymarin-loaded chitosan/gelatin/hyaluronic acid hybrid constructs for advanced full-thickness burn wound management,” Int. J. Pharm., vol. 659, p. 124238, Jun. 2024, doi: 10.1016/j.ijpharm.2024.124238
103. Shukla, P., Srivastava, P. & Mishra, A. On the potential activity of hyaluronic acid as an antimicrobial agent: experimental and computational validations. Bioprocess Biosyst Eng (2024). https://doi.org/10.1007/s00449-024-03091-4
102. Abhay Dev Tripathi, Yamini Labh, Soumya Katiyar, Vivek K. Chaturvedi, Abha Mishra*. “Advancements in Nano-Mediated Biosensors: Targeting Cancer Exosome Detection.” Journal of Cluster Sciences, Aug 2024 DOI: 10.1007/s10876-024-02676-z, Impact factor 2.8
101. Soumya Katiyar, Abhay Dev Tripathi, Ritika K. Singh, Avinash Kumar Chaurasia, Pradeep K. Srivastava, Abha Mishra*, Graphene-silymarinloaded chitosan/gelatin/hyaluronic acid hybrid constructs for advanced full-thickness burn wound management, International Journal of Pharmaceutics, /doi.org/10.1016/j.ijpharm.2024.124238 Impact factor 5.3
100. AbhayDev Tripathi, Yamini Labh, Soumya Katiyar, Anurag Kumar Singh, Vivek K. Chaturvedi, and Abha Mishra*; Folate-MediatedTargeting and ControlledRelease: PLGA-Encapsulated MesoporousSilica NanoparticlesDelivering Capecitabineto Pancreatic Tumor, ACS Appl. Bio Mater, doi.org/10.1021/acsabm.4c00019, Impact factor 3.25
2023
99. Abhay D Tripathi, Soumya Katiyar and Abha Mishra*; Glypican1: a potential cancer biomarker for nano-targeted therapy, Drug discovery Today, Jun 9;103660.doi: 10.1016/j.drudis.2023.103660, 2023 IF 8.369
98. Ravi Saini, Sonali Kumari, Amit Singh and Abha Mishra*,From nature to cancer therapy: Evaluating the Streptomyces clavuligerus secondary metabolites for potential protein kinase inhibitors JCB_EV_JCB30501, J of Cellular Biochemistry, Wiley, DOI: 10.1002/JCB, 30501.IF4.481
97. Sonali Kumari, Ravi Saini, Abha Mishra*, Phytochemical profiling and evaluation of the antidiabetic potential of Ichnocarpus frutescens (Krishna Sariva): Kinetic study, molecular modelling, and free energy approach, Journal of Biomolecular Structure and Dynamics, 2023 Aug 24:1-20. doi: 10.1080/07391102.2023.2248265. Epub ahead of print. PMID: 37615387., Impact factor 5.23
96. Sonali Kumari, Ravi Saini, Abha Mishra*,Exploring Plant-Based Alpha-Glucosidase Inhibitors: Promising Contenders for Combatting Type-2 Diabetes" Archives of Physiology and Biochemistry. DOI: 10.1080/13813455.2023.2262167; 2023, IF 3.188
95. Sonali Kumari, R Saini, A Bhatnagar and Abha Mishra*, HRLCMS based metabolite profiling, Antioxidant and hypoglycaemic properties of Daruharidra (Berberis aristata): molecular modelling and in vitro approach. New J of Chemistry, Royal Society of Chemistry,2024, New J. Chem., 2024,48, 578-590 IF 3.98
94. Virendra Singh, Ravi Mehra, Kirtan Babu Ramesh, Pradeep Kumar Srivastava, Abha Mishra*, Treatment of carpet and textile industry effluents using Diplosphaera mucosa VSPA: A multiple input optimisation study using artificial neural network-ge‐ netic algorithms; Bioresource Technology, Available online 6 August 2023, 129619, https://doi.org/10.1016/j.biortech.2023.129619, Impact factor 11.88
93. Aditi Bhatnagar and Abha Mishra*; Development of Daruharidra (Berberis aristata) based biogenic Cadmium sulfide nanoparticles: Its implementation as an antibacterial and novel therapeutic agent against human breast and ovarian cancer. Current Pharmaceutical Biotechnology, Bentham Science Publishers (17Nov 2023) DOI: 10.2174/0113892010244977231108043554 Impact factor 2.82
92. Sonali Kumari, R Saini, A Bhatnagar and Abha Mishra*,Phytochemical profiling and evaluation of the antidiabetic potential of Ichnocarpus frutescens (Krishna Sariva): Kinetic study, molecular modelling, and free energy approach, Journal of Biomolecular Structure and Dynamics, 2023 Aug 24:1-20. doi: 10.1080/07391102.2023.2248265. Epub ahead of print. PMID: 37615387., Impact factor 5.23
91. Virendra Singh, Pradeep Kumar Srivastava, Abha Mishra* Exploring the potential of Diplosphaera mucosa VSPA for the treatment of petroleum effluent with simultaneous lipid production, Environmental Science and Pollution Research, 2023 August 2023, 30(43)DOI:10.1007/s11356-023-29228-8 Impact factor 5.19
90. Sonali Kumari, Ravi Saini, Abha Mishra*, A comprehensive review on Ayurvedic herb Leptadenia reticulata (Jeevanti)-A phytochemistry and pharmacological perspective. Natural Product Research. 10.1080/14786419.2023.2282119© 2023 Informa UK Limited, Taylor & Francis Group. IF 2.488
89. Shikha Kumari, Abha Mishra, Divakar Singh, Chenzhong Li, Pradeep Srivastava, In-vitro Studies on Copper Nanoparticles and Nano-hydroxyapatite Infused Biopolymeric Composite Scaffolds for Bone Bioengineering Applications, Biotechnology and Bioprocess Engineering, 28 (1), 162-180, 2023. 2, 2023. IF 2.3
88. Ravi Saini, Sonali Kumari, Aditi Bhatnagar, Amit Singh, Abha Mishra**, Discovery of the allosteric inhibitor from actinomyces metabolites to target EGFR CSTMLR mutant protein: Molecular modelling and free energy approach", Scientific Reports, Nature Portfolio; https://doi.org/10.1038/s41598-023-33065-7; (2023) 13:8885; IF 4.997
87. Priya Shukla, P Srivastava and Abha Mishra**, Downstream process intensification for biotechnologically generated hyaluronic acid: purification and characterization on June 09, 2023. Journal of Bioscience and Bioengineering: https://doi.org/10.1016/j.jbiosc.2023.06.003. IF 3.185
86. Virendra Singh, Pradeep Srivastava , Abha Mishra*, Design and modelling of photobioreactor for the treatment of carpet and textile effluent using Diplosphaera mucosa VSPA, 3 Biotech, Springer (2023) jan, 13:235 https://doi.org/10.1007/s13205-023-03655-3 IF 3.446
85. Aditi Bhatnagar and Abha Mishra*, Biogenic Synthesis of Cadmium Sulfide Nanoparticles Using Daruharidra (Berberis aristata) and Its Implementation as a Novel Therapeutic Agent against Human Breast and Ovarian Cancer;Research Article - (2023) Volume 7, Issue 2; DOI: 10.21767/IPIPR.23.7.012J of Pharmacy and Pharmaceutical Research.
84. Katiyar S, Singh D, Kumari S, Srivastava P, Mishra A. Novel strategies for designing regenerative skin products for accelerated wound healing. 3 Biotech. 2022 Nov;12(11):316. doi: 10.1007/s13205-022-03331-y. Epub 2022 Oct 8. PMID: 36276437; PMCID: PMC9547767. IF 3.446
83. Deepankar Sharma , Abha Mishra* , Synergistic effects of ternary mixture formulation and process parameters optimization in a sequential approach for enhanced L-asparaginase production using agro-industrial wastes; Environmental Science and Pollution Research Pub Date: 2023-04-22 , DOI:10.1007/s11356-023-26977-4; ( IF 5.19 )
82. Virendra Singh, Abha Mishra*, Pradeep Srivastava, Textile and domestic effluent treatment via co-cultivation of Diplosphaera mucosa VSPA and Scenedesmus obliquus, Biomass and Bioenergy,Volume 172, May 2023, 106756, ISSN 0961-9534, https://doi.org/10.1016/j.biombioe.2023.106756. IF 5.774
81. Priya Shukla, P Srivastava and Abha Mishra*, Tapping on the potential of Hyaluronic acid: From production to application. Appl Biochem, Biotechnol, Springer. 2023 Mar 24.doi: 10.1007/s12010-023-04461-6.IF 2.434
80. D Sharma and A Mishra; Apoptosis induction in leukemic cells by a novel L-asparaginase preparation from Bacillus indicus: bench-scale production, purification and therapeutic application"3Biotech 2023 Jan;13(1):21. doi: 10.1007/s13205-022-03440-8. Epub 2022 Dec 21. IF3.446
2022
79. Shikha Kumari, Divakar Singh, Pradeep Srivastava, Bhisham Narayan Singh and Abha Mishra*, Generation of graphene oxide and nano-bioglass based scaffold for bone tissue regeneration30 September 2022 Biomedical Materials, Volume 17, 065012, Impact factor 4.347
78. Katiyar, S., Singh, D., Kumari, S. P Srivastava, Abha Mishra*,. Novel strategies for designing regenerative skin products for accelerated wound healing. 3 Biotech 12, 316Nov (2022). https://doi.org/10.1007/s13205-022-03331-y Impact factor 3.446
77. Shikha Kumari, Soumya Katiyar, Darshna Darshna, Aditya Anand, Divakar Singh, Bhisham Narayan Singh, Sarada Prasanna Mallick, Abha Mishra*, Pradeep Srivastava, Design Strategies for Composite Matrix and multifunctional polymeric scaffolds with enhanced Bioactivity for Bone Tissue Engineering; Frontiers in Chemistry, section Nanoscience, 28Nov2022,Vol10 DOI.Org/10.3389/fchem.2022.1051678 IF 5.221
76. Shikha Kumari, Pradeep Srivastava, Abha Mishra*, Generation of bioactive porous chitosan/gelatin based scaffold modified with Tri-calcium phosphate/nano-bioglass for Bone tissue engineering applications" Dec 2022,J of Porous Materials, Springer DOI:10.1007/s10934-022-01406-y IF 2.496
75. Priya Dagar1 and Abha Mishra*, Anti-cancer and Anti venom analysis of a Natural Compound. Current Bioactive Compounds, Bentham Science Publishers 1Oct2022, doi.org/10.2174/1573407218666221011092257 IF 1.04
74. Priya Dagar1 and Abha Mishra*, Herbal Compounds as an Antidote Against Snake Bite, Current Pharmaceutical Design, doi.org/10.2174/1381612828666220417134118, 2022;28(21):1714-1719. Jun2022 Impact factor 3.116
73. Priya Shukla, P Srivastava and Abha Mishra*, Hyaluronic Acid Production by Utilizing Agro-industrial Waste Cane Molasses", 3 Biotech Vol12, no.9,pp208; ISSN2190-572X 2022. Impact factor 2.89
72. A Singh, A Mishra, Molecular modelling study to discover novel JAK2 signaling pathway inhibitor, DOI: 10.1080/07391102.2022.2097314 2022, J Biomol Struct Dyn 2023 Jul-Aug;41(12):5827-5838 Epub 2022 Jul Journal of Biomolecular Structure and Dynamics,, 1-12, Impact factor 5.23
71. Priya Dagar, Abha Mishra*, Molecular modeling and in vitro studies of gedunin a potent alpha-amylase inhibitor and alpha-glucosidase inhibitorResearch Communication, Biofactors, Wiley,24 May 2022,https://doi.org/10.1002/biof.1846 Impact factor 6.11
70. Abha Mishra* and Amit Singh, Discovery of Histone Deacetylase Inhibitor Using Molecular Modeling and Free Energy Calculations; ACS Omega 2022 7 (22),18786-18794DOI: 10.1021/acsomega.2c01572 Impact factor 4.132
69. Amit Singh & Abha Mishra*, Investigation of Molecular Mechanism Leading to Gefitinib and Osimertinib Resistance Against EGFR tyrosine Kinase: Molecular Dynamics and Binding Free Energy Calculation, Journal of Biomolecular Structure and Dynamics, Jul;41(10):4534-4548. doi: 10.1080/07391102.2022.2068650. 2022 Impact factor 5.23
68. Reena Visvakarma, Abha Mishra**, Characterization of a novel protease inhibitor abpi from the edible mushroom Agaricus bisporus, Protein and Peptide Letters. 2022 Apr 5. doi: 10.2174/0929866529666220405161903. 2022. Impact factor 1.89
67. Aditi Bhatnagar, Ravi Saini, Priya Dagar & Abha Mishra**, Molecular modelling and in vitro studies of Daruharidra as a potent alpha-amylase Inhibitor, Journal of Biomolecular Structure and Dynamics, https://doi.org/10.1080/07391102.2022.2058093,2022, 2023 Jun;41(9):3872-3883. Impact factor 5.23
66. Amit Singh, Ravi Saini & Abha Mishra**, Novel allosteric inhibitor to target drug resistance in EGFR mutant: molecular modelling and free energy approach, Molecular Simulation, March 2022, 48(3):1-11Taylor and Francis,10.1080/08927022.2022.2055012.2022 Impact factor 2.178
65. Sharma D & Abha Mishra**, Natural Phytocompounds Physalin D, Withaferin A and Withanone target L-asparaginase of Mycobacterium tuberculosis: A molecular dynamics study, Journal of Biomolecular Structure and Dynamics, 2023 Apr;41(7):2645-2659.https://DOI: 10.1080/07391102.2022.2036239 2022 Impact factor 5.23
2021
64. Sharma D & Abha Mishra**, L-asparaginase production in solid-state fermentation using Aspergillus niger: process modeling by artificial neural network approach, Preparative Biochemistry & Biotechnology 1-12, https://doi.org/10.1080/10826068.2021.1972426, 2021. Impact factor 2.162
40. Priya Dagar & Abha Mishra**, Molecular docking analysis of modified gedunin from neem with snake venom enzymes, Bioinformation, sept 17(9): 776-783; ISSN 0973-2063 (online) 0973-8894,2021
63. Dhiraj Kumar Choudhary, Navaneet Chaturvedi, Amit Singh & Abha Mishra**, Catechin isolated from faba beans (Vicia faba L.): insights from oxidative stress and hypoglycemic effect in yeast cells through confocal microscopy, flow cytometry, and in silico strategy, Journal of Biomolecular Structure and Dynamics, https://doi.org/10.1080/07391102.2021.1945953,2021. Impact factor 5.23
2020
62. Abha Mishra*, U Kaur and A Singh, Fisetin 8-C-glucoside as entry inhibitor in SARS CoV-2 infection: molecular modelling study, Journal of Biomolecular Structure and Dynamics, doi: 10.1080/07391102.2020.1868335,2020. Impact factor 5.23
61. A Singh, Abha Mishra*, Molecular dynamics simulation and free energy calculation studies of Coagulin L as dipeptidyl peptidase-4 inhibitor, Journal of Biomolecular Structure and Dynamics doi.org/10.1080/07391102.2020.1822917,2020, Impact factor 5.23
60. A Singh and Abha Mishra**, Leucoefdin a potential inhibitor against SARS CoV-2 Mpro, Journal of Biomolecular Structure and Dynamics, 2021 Volume: 39, Issue: 12, pp 4427-4432DOI: 10.1080/07391102.2020.1777903, 2020. Impact factor 5.23
59. Dhiraj Kumar Choudhary, Navaneet Chaturvedi, Amit Singh and Abha Mishra**,Investigation of hypoglycemic effects, oxidative stress potential and xanthine-oxidase activity of polyphenols (gallic acid, catechin) derived from faba bean on 3T3-L1 AQ5 cell line: insights into molecular docking and simulation study, Royal Society of Chemistry, Toxicology Research, 1–14 doi: 10.1093/toxres/tfaa025 Oxford Press,2020. Impact factor 3.983
58. Reena Vishvakarma and Abha Mishra**, Effect of protease inhibitor from Agaricus bisporus on glucose uptake and oxidative stress in 3T3-L1 adipocytes, Asian Pac J Trop Biomed 2020;10:136-146DOI: 10.4103/2221-1691.276319 2020. Impact factor 1.226
57. Choudhary DK, Chaturvedi N, Singh A, Abha Mishra**, Characterization, inhibitory activity and mechanism of polyphenols from faba bean (gallic-acid and catechin) on α-glucosidase: insights from molecular docking and simulation study. Prep Biochem Biotechnol. 2020;50(2):123-132. doi:10.1080/10826068.2019.1679171, 2020. Impact factor 2.162
56. Chaturvedi N, Abha Mishra*, and V Rawat, Synthesis and Characterization of Oxygen Depleted tert-Amine Calix[4]arene Ligands and Study the Effect on Sigma Non-Opioid Intracellular Protein ReceptorStructural Chemistry Structural Chemistry, https://doi.org/10.1007/s11224-019-01324-x , 2019. Impact factor 1.78
2019
55. Reena Vishvakarma and Abha Mishra**, Protective effect of a protease inhibitor from Agaricus bisporus on Saccharomyces cerevisiae cells against oxidative stress, Preparative Biochem and Biotechnology, (1 0.1080/10826068.2018.1536992, 2019. Impact factor 2.162
54. Sonkar SC, Abha Mishra*, and Navaneet Chaturvedi, A Road-map to Tackle the Challenges of Antimicrobial Resistance: Act Today for Better Tomorrow,EC MICROBIOLOGY,Perspective 15.10, 1154-1156, 2019.
53. S Kashyap, A Singh, Abha Mishra*, V Singh. Enhanced sustained release of furosemide in long circulating chitosan conjugated PLGA nanoparticles, Research in Pharmaceutical Sciences 14 (2), 93-106, 2019,. Impact factor 3.13
52. Dhiraj Kumar Choudhary & Abha Mishra**, In vitro investigation of hypoglycemic and oxidative stress properties of fava bean (Viciafaba L.) seed extract in Saccharomyces cerevisiae 2376 Preparative Biochem and Biotechnology, (ISSN: 1082-6068 (Print) 1532-2297 (DOI: 10.1080/10826068.2018.1525560, 2018 Impact factor 2.16
2018
51. Choudhary Dhiraj Kumar, Abha Mishra**, and Mittal Aishwarya,Exploring hypoglycemic potential of Vicia faba crude seed extract in Saccharomyces cerevisiae 3187,Res. J. Biotech , Vol. 13 (7) 2018.
50. Sharma D, Singh K, Singh K and Abha Mishra**, Insights into the microbial L-asparaginases: from production to practical applications Current Protein and Peptide Science, 2019, 20, 1-13; DOI:10.2174/1389203720666181114111035, 2018. Impact factor 3.272
49. Choudhary Dhiraj Kumar, Abha Mishra*, and Mittal Aishwarya,Exploring hypoglycemic potential of Vicia faba crude seed extract in Saccharomyces cerevisiae 3187,Res. J. Biotech , Vol. 13 (7) 2018.
48. Sharma D, Singh K, Singh K and Abha Mishra*, Insights into the microbial L-asparaginases: from production to practical applications Current Protein and Peptide Science, 2019, 20, 1-13; DOI:10.2174/1389203720666181114111035, 2018. Impact factor 3.272
47. Kushagri Singh, Abha Mishra*, Deepankar Sharma, Kavita Singh, Nanotechnology in Enzyme Immobilization: An Overview on Enzyme Immobilization with Nanoparticle Matrix,Current Nanoscience, 15, 1-8 DOI : 10.2174/1573413714666181008144144, 2018. Impact factor 1.824
46. Ekant Tamboli, Aditi Bhatnagar and Abha Mishra*, Alpha-amylase inhibitors from mycelium of an oyster mushroom, Prep BiochemBiotechnol. 17:1-7. doi: 10.1080/10826068.2018.1487849, 2018. Impact factor 2.162
45. Dhiraj Kumar Choudhary & Abha Mishra*, In vitro and in silico interaction of faba bean (Viciafaba L.) seed extract with xanthine oxidase and evaluation of antioxidant activity as a therapeutic potential Natural Product Research https://doi.org/10.1080/14786419.2018.1460831, Taylor a& Francis, 2019. Impact factor 2.861
44. VKYadav and Abha Mishra*, In vitro & in-silico study of hypoglycemic potential of Pterocarpus marsupium heartwood extract Natural Product Resarch, Taylor and Francis May 4:1-5. doi: 10.1080/14786419.1471078, 2018. Impact factor 2.861
43. K Singh ,Amit Singh and Abha Mishra*, Synthesis characterization and in vitro release study of ciprofloxacin loaded chitosan nanoparticle, BioNano Science, Springer, Volume 8, Issue 1, pp 229–236, March 2018. Impact factor 2.305
2017
42. Reena Viswakarma and Abha Mishra*, Production of a protease inhibitor from edible mushroom Agaricusbisporus and its statistical optimization by Response Surface Methodology Preparative Biochemistry and Biotechnology ISSN: 1082-6068 (Print) 1532-2297 (Online) Journal homepage: http://www.tandfonline.com/loi/lpbb20, 2017. Impact factor 2.162
41. Pandey, Usha; Pandey, Jitendra; Singh, Anand V.; Abha Mishra, Anthropogenic drivers shift diatom dominance–diversity relationships and transparent exopolymeric particles production in River Ganga: implication for natural cleaning of river water , CURRENT SCIENCE, Volume 113 - Issue 05,959-964.Ind Acad of Sci, 2017. Impact factor 1.1
40. Dhiraj Kr Choudhary and Abha Mishra*, In vitro and in silico interaction of procine alpha amylase with Viciafaba crude seed extract and evaluation of antidiabetic activity, Bioengineered ((4): 393–403.) Taylor & FrancisISSN: 2165-5979 (Print) 2165-5987 (Online) Journal homepage: http://www.tandfonline.com/loi/kbie20 , 2017. Impact factor 3.2
2015
39. K Singh and Abha Mishra*, Chitosan Nanoparticulate And Their Applications: A Review,Ijpbs,6(2) 557-566,2015.
38. K Singh, Abha Mishra*, A Singh, Preparation and In Vitro Characterization of Chitosan Nanoparticles Containing Amphotericin B as a Drug Delivery System, Advanced Science Letters, Volume 21, Number 8, 2606-2608(3) 2015. Impact factor 1.2
37. Sharad Verma, Amit Singh and Abha Mishra*, Complex disruption effect of natural polyphenols on Bcl-2-Bax: Molecular dynamics simulation and essential dynamics study, J Biomol Struct Dyn. 33(5):1094-106. doi: 10.1080/07391102.2014.931823. Epub, 2015. Impact Factor 5.2
2014
36. K Singh and Abha Mishra* ,Gelatin Nanoparticle: Preparation, characterisation And Application In Drug Delivery(Review) International Journal of Pharmaceutical sciences and ResearchVol. 5, Issue 06; 2014.
35. Amit Singh, Surendra Pratap Mishra, Abha Mishra, Effect of Ginkgobiloba on Renal Ischemia-Reperfusion Induced Oxidant Stress In Rats.RRJPTS | Volume 2 | Issue 1 | January - March, 2014.
34. Amit Singh, Abha Mishra, Sharad Verma, Vinay Purohit and Raj Kumar Goel,MMPs as molecular targets for wound healing by OcimumSanctum: in silico and in vivo evidences.IJBCP. Vol3, Issue1,1-7, 2014.
33. Amit Singh, Surendra Pratap Mishra, Abha Mishra, Comparative Study of Assay of Free Radical Damage in In Vivo, In Vitro and Ex Vivo Conditions.IJBCP. (doi: 10.5455/2319-2003.ijbcp20140411),2014.
32. Sharad Verma, Amit Singh, Abha Mishra*, Gallic acid: Molecular rival of cancer. Environmental Toxicology and Pharmacology. 35, 473–485, 2013. Impact factor 4.8
31. Sharad Verma, Amit Singh and Abha Mishra*, Molecular dynamics investigation on the poor sensitivity of A171T mutant NEDD8-activating enzyme (NAE) for MLN4924 Journal of Biomolecular Structure & Dynamics.Taylor& rancishttp://dx.doi.org/10.1080/07391102.2013.804436, 2014. Impact Factor 5.23
2013
30. Sharad Verma, Amit Singh and Abha Mishra*, The effect of fulvic acid on pre and post aggregation state of Aβ17-42: Molecular dynamics simulation studies,Biochimica et Biophysica Acta (BBA – Proteins and Proteomics), 1834 24–33, 2013. Impact factor 3.0
29. Abha Mishra*, Response to Horn and Kahler. (PMID:24084293) Biochimica et Biophysica Acta[2013, 834(12):2869]Type:Comment, LetterDOI:0.1016/j.bbapap.2013.07.013, 2013. Impact factor 3.036
28. Sharad Verma, Amit Singh, Nidhi Goyal and Abha Mishra*, A Molecular Dynamics Investigation on the Inhibition of PRL-3 by Emodin, International Journal of Drug Design and Discovery 3(4)879-885, ISSN 0975-4423, 2013.
27. Swet Chand Shukla and Abha Mishra*, ε-PolyLysine production from sugar cane molasses by new isolates of Bacillus sp., and optimization of fermentation condition Annals of Microbiology, Springer, DOI:10.1007/s13213-013-0615-z; (63),4: 1513–1523, 2013. Impact Factor 2.11
26. Kushagri Singh, Abha Mishra*, Water Soluble Chitosan Nanoparticle For The Effective Delivery Of Lipophilic Drugs: A Review International Journal of Applied Pharmaceutics ISSN- 0975-7058 Vol 5, Issue 3, 2013.
25. Sharad Verma, Amit Singh and Abha Mishra*, Molecular dynamics investigation on the inhibition of MDM2-p53 interaction by polyphenols, Molecular Informaticsvol32(2)203-212 Elsevier, 2013. Impact Factor 3.35
2012
Swet Chand Shukla, Amit Singh, Abha Mishra*, Review on microbial Production of epsilon polylysine and its medical application, Biochemical Engg. Journal 65,70-81, 2012. Impact Factor 3.97
24. Sharad Verma, Amit Singh and Abha Mishra*, Dual inhibition of chaperoning process by Taxifolin: Molecular dynamics simulation study, Journal of Molecular Graphics and Modelling, 37, 27-38 , 2012. Impact Factor 2.518
23. Sharad Verma, Amit Singh and Abha Mishra*, Quercetin and taxifolin completely break MDM2–p53 association: molecular dynamics simulation study, Medicinal Chemistry Research, SpringerDOI 10.1007/s00044-012-0274-9,2012. Impact Factor 2.351
22. Abha Mishra*, and Sharad Verma, Optimization of process parameters for tacrolimus (FK506) production by new isolate of Streptomyces sp. Using response surface methodology, Journal of Biochemical Technology. ISSN:0974, 2012.
21. Sharad Verma, Amit Singh and Abha Mishra*, Taxifolin acts as type I inhibitor for VEGFR-2 kinase: Stability evaluation by molecular dynamic simulation, Journal of Applied Pharmaceutical Science, 02 (01) 41-46 ISSN:2231-3354, 2012.
20. Amit Singh, Abha Mishra*, Sharad Verma et al, MMPs as Molecular Targets for Wound Healing by Musa sapientum: In-silico and In-vivo Evidences, Research And Reviews: Journal Of Pharmacology And Toxicological Studies, Rrjpts | Volume 2 | Issue 1 | January - March, 2014.
19. AK Pandey, S Verma, P Bhattacharya, S Paul, Abha Mishra, R Patnaik, An in-silico strategy to explore neuroprotection by quercetin in cerebral ischemia: A novel hypothesis based on inhibition of matrix metalloproteinase (MMPs) and acid sensing ion channel 1a (ASIC1a),Medical Hypotheses,79 (1) 76-81,2012. Impact Factor 1.53
18. Sharad Verma, Amit Singh and Abha Mishra*, Molecular construction of NADH-cytochrome b5 reductase inhibition by flavonoids and chemical basis of difference in inhibition potential: Molecular dynamics simulation study,Journal of Applied Pharmaceutical Science, 02 (08)ISSN:2231-3354 , 2012.
17. Arunima Kumar Verma, Shipra Gupta, Sharad Verma, Abha Mishra, N.S. Nagpure, Interaction between shrimp and White Spot Syndrome Virus through PmRab7-VP28 complex: an insight using simulation and docking studies, Journal of Molecular Modeling, Springer , 2012. Impact Factor 1.8
16. Sharad Verma, Amit Singh and Abha Mishra*, Molecular insight in to the selective inhibition of Phosphodiesterase 5A by fulvic acid (principal constituent of shilajit): Molecular dynamics simulation evidences,International Journal of Drug Design and Discovery 3(4)879-885, ISSN 0975-4423 ,2012.
15. Sharad Verma, Amit Singh and Abha Mishra*, Taxifolin inhibits GTP binding in wild and Apo forms of Ras: Molecular docking and molecular dynamics simulation study, J of Biochem Technology, 3(4), ISSN:0974-2328, 2012.
14. Abha Mishra*, S Verma ,Optimization of process parameters for tacrolimus (FK 506) production by new isolate of Streptomyces sp. using response surface methodology (RSM) Journal of Biochemical Technology, J Biochem Tech 3(4):419-425 ISSN:0974-238, 2012.
13. Amit Singh, Abha Mishra, Sharad Verma et al., Regulation of wound strength by Curcuma longa: in silico and in vivo evidences, Journal of Pharmacy Research, 5(9), 4734-4738 ISSN: 0974-6943,2012.
2011
12. Sudhir Kumar and Abha Mishra*, Optimization of laccase production from WRF-1 on groundnut shell and cyanobacterial biomass: By application of Box-Behnken experimental design,J Microbiol Biotech Res, 1 (2) 33-53(2011) ISSN: 2231-3168, 2011.
11. Abha Mishra*, Kumar Sudhir and Pandey Anand Kumar,Laccase production and simultaneous decolorization of synthetic dyes in unique inexpensive medium by new isolates of white rot fungus International Biodeterioration and Biodegradation, 65(3) 487-494,2011. Impact Factor 4.32
2009
10. Abha Mishra*, and Sudhir Kumar,Kinetic studies of laccase enzyme of Coriolus versicolor MTCC138 in an expensive culture medium, BiochemicalEngg. Journal 46, 252-256,2009. Impact Factor 3.97
9. Abha Mishra*, Sunil Kumar and Sudhir Kumar,The application of Box-Bekhen Experimental Design for optimization of laccase production by Coriolus versicolor MTCC138 in solid state fermentation Journal of Scientific and Industrial Research 67, 1098-1107,2008. Impact Factor 1.5
2007
8. Abha Mishra*and Sunil kumar, Cyanobacterial biomass as N-supplement to agro-waste for hyper-production of Laccase from Pleurotus ostreatus in solid state fermentation, Process Biochemistry 42(4); 681-685,2007. Impact Factor 3.75
2006
7. A Mishra*, Production of L-Asparaginase an anticancer agent from Aspergillus niger using agricultural waste in Solid State Fermentation, Applied Biochemistry and Biotechnology, 135(1);33-42,2006. Impact Factor 2.43
2005
6. A Mishra*, and U. Pandey, Effects of agriculturally important microorganisms on growth of medicinal plant “Mentha piperata”, Indian Journal of Applied and Pure Biology, XX (1);19-22; ISSN0970-2091 ,2005.
2003
5. Abha Mishra and M. D. Das*, Studies on effect of nutrients on glucose isomerase production by Streptomyces griseus NCIM2020,Asian Journal of Microbiology,Biotechnology and Environ Sci, 5(1); 91-96; ISSN0572-3005,2003.
2002
4. A Mishra*, and M. D. Das, Effect of pH on simultaneous saccharificationand isomer-ization by glucoamylase and glucose isomerase, Applied Biochemistry and Biotechnology,102-103; 193-199, 2002. Impact Factor 2.43
2001
3. A Mishra*, and M. Debnath (Das),The production of glucoamylase by Aspergillus oryzae MTCC 152 in Solid State Fermentation, I Journal of Microbiology, 41;191-193 ,2001.
1998
2. A Mishra*, and U. Pandey,Effect of phosphorus and boron compounds on the production of cephalosporin-C acylase by two strains of bacteria, Journal of Ecotoxicology and Environmental Monitoring, 8 (4); 233-238 ISSN:0971-0965-0008-98-233, 1998. , Impact score 3.73
1. U. Pandey* and Abha Mishra,Cu2+ and Cd2+ Uptake and their localization in cyanobacterium Anacystis nidulans, Journal of Ecotoxicology and Environmental Monitoring, 8 (3);179-182 ISSN:0971-0965-0008-98-233,1998.
Ph.D.s as a Supervisor- 10 as Supervisor (awarded); 02 submitted; 04 ongoing
Ph.D. students Co-guided: 09 (04-awarded; 05-ongoing)
PG dissertation guided-55 Awarded; 04 ongoing
Current members
|
Name of students |
Submitted/ongoing |
Course |
Broad Research Area |
|
Abhay Dev Tripathi |
Ongoing |
PhD |
Phytochemicals for the drug discovery against cancer |
|
Sonali Kumari |
Ongoing |
PhD |
Therapeutic potential of Ichnocarpus frutescens and Hemidesmus indicus |
|
Shruti R Raut |
Ongoing |
PhD |
Hydrogen production |
|
Arpit Sharma |
Ongoing |
PhD |
Translational Hemato-Oncology |
|
Ravi Yadav |
Ongoing |
PhD |
Value added product from microalgae |
|
Aishwarya Kesari |
Ongoing |
PhD |
Synthesis of scaffolds for tissue engineering |
|
Deepak Yadav |
Ongoing |
M.Tech |
Graphene Nanomaterials |
List of Projects:
|
S.No. |
Project title |
Funding agency |
Status (Ongoing/completed/ Submitted) |
|
1. |
Production of epsilon poly lysine and its specific conjugates for effective drug targeting, |
DRDO |
Completed |
|
2. |
Studies on production and properties of glucoamylase by some new isolates of Aspergillus oryzae using agro-industrial waste in solid state fermentation, |
UGC |
Completed |
|
3. |
Targeted drug delivery of methotrexate / gallic acid folate conjugated Poly L-Lysine nanoparticles |
DBT |
Completed (Sept 2018-Sept 2021) |
|
4. |
Transcriptome analysis of Cancer cell line treated with Gedunin and ZINC000045971961 as novel Bruton’s tyrosine kinase (BTK) inhibitor |
LSRB, DRDO
|
Ongoing (June 2023- July 2026) |
|
5. |
Designing and fabrication of norfloxacin cunps and EGF loaded multilayered wound dressing for diabetic burn wound |
CSIR |
Ongoing (Sept 2024-Sept 2026) |
|
6. |
Development of a nanostructured graphene oxide/polydopamine coated nano-biosensor monitoring GPC1 for the early diagnosis of pancreatic cancer, |
ICMR |
Ongoing (Nov 2024-Nov 2027) |
List of Book Chapters:
14. Raut, S.S., Mishra, A. (2024). Gamma Radiation-Based Technologies for Waste Biomass Valorization: Mechanism, Instrument Design, Recent Technical Advances, Limitations, and Future Aspect. In: Verma, P., Kumar, B. (eds) Sustainable Radiation Technologies in Waste-biomass Valorization. Green Chemistry and Sustainable Technology. Springer, Cham. https://doi.org/10.1007/978-3-031-63941-8_10
13. Sharma, A., Raut, S.S., Dhikale, P., Khushboo, Mishra, A. (2024). Navigating the Landscape of Cancer-Induced Thrombocytopenia: Current Challenges and Emerging Advances. In: Verma, P. (eds) Industrial Microbiology and Biotechnology. Springer, Singapore. https://doi.org/10.1007/978-981-97-6270-5_14
12. Priya Shukla, Pradeep Srivastava and Abha Mishra*(Corres auth); Chapter Title : Hyaluronic Acid Microbial Synthesis and Its Explicit Uses in the Development of Nutraceuticals, Biomedicine, and Vaccine Development. Industrial Microbiology and Biotechnology, Springer, Nature, DOI : 10.1007/978-981-99-2816-3
11. Priya Shukla, Pradeep Srivastava and Abha Mishra*(Corres auth); Chapter Title : New Developments in the Production and Recovery of Amino Acids, Vitamins, and Metabolites from Microbial Sources; Industrial Microbiology and Biotechnology, Springer, Nature DOI : 10.1007/978-981-99-2816-3
10. Bhatnagar, A., Mishra, A. (Corres auth) (2022). α-Glucosidase Inhibitors for Diabetes/Blood Sugar Regulation. In: Maheshwari, V.L., Patil, R.H. (eds) Natural Products as Enzyme Inhibitors. Springer, Singapore. https://doi.org/10.1007/978-981-19-0932-0_122.2
9. Soumya Katiyar, Shikha Kumari, Abhay D Tripathi, Ritika Singh, Divakar Singh, Pradeep Srivastava, Abha Mishra* (Corres auth), Recent advances of the nanobiosensor in tissue engineering, Chapter; in the book Recent advances in Biosensor Technology (vol1) Bentham Science ISBN: 978-981-5123-74-6 (Print),ISBN: 978-981-5123-73-9 (Online),2023DOI:10.2174/97898151237391230101
8. Sonali Kumari, Ravi Saini,Aditi Bhatnagar and Abha Mishra* (corres author)Ichnocarpus frutescens and Its Role in Alpha-Glucosidase Inhibition ; Alpha-Glucosidase and its Role in Human Disease; 24099, 2023 in Press
7. A D Tripathi, S Katiyar and Abha Mishra*(corres author),The emerging role of biosensors in the identification, characterization, and use of Natural Bioactive compounds; Bentham Science (Book- Recent Advances in Biosensor Technology, ISBN: 978-981-5123-74-6 (Print),ISBN: 978-981-5123-73-9 (Online), 2023
6. A D Tripathi, S Katiyar and Abha Mishra*(corres author),Nanomaterials for Biosensing Applications Bentham Science (Book- Recent Advances in Biosensor Technology, ISBN: 978-981-5123-74-6 (Print),ISBN: 978-981-5123-73-9 (Online), 2023
5. Usha Pandey and Abha Mishra*, A Protein-Legand Interaction Of Cyanobacterial Toxin Microcystin Lr, A Novel Inhibitor Of Bacterial Pathogen, Journal of Scientific Research, ISSN : 0447-9483,2019,
4. Green synthesis of nanoparticles by endophytes Endophytic Association: What, Why and How,; Endophytic Association: What, Why and How Developments in Applied Microbiology and Biotechnology; A Bhatnagar, A Mishra(corres author), 487-502, 2022
3. Sumedha Shah, Dr. Abha Mishra*(Corres auth) Treatment Technologies for Addressing the Removal of Industrial Effluents Affecting the Quality of River Ganges in Eastern part of Uttar Pradesh; Combined Application of Physico-Chemical & Microbiological Processes for Industrial Effluent Treatment Plant, SpringerOnline 978-981-15-0497-6,2019.
2. Abha Mishra* (Corres auth) Sudhir Kumar, Aditi Bhatnagar, Chapter 7 - Potential of Fungal Laccase in Decolorization of Synthetic Dyes; Microbial Wastewater Treatment, Elsevier978-0-12-816809-7,2019.
1. Kushagri Singh, Abha Mishra* (Corres auth), Deepankar Sharma, Kavita Singh, Applications of Targeted Nano Drugs and Delivery Systems; Nanoscience and Nanotechnology in Drug Delivery,Micro and Nano Technologies,Pages 343-356;Chapter13; Antiviral and Antimicrobial Potentiality of Nano Drugs Elsevier B97, 8-0-12-814029-1.000-2, 2019.
Previous Lab Members:
|
Name of Ph.D. students |
Submitted/ongoing |
Title of Thesis |
|
2012 |
Production and properties of laccase enzyme and its potential application in decolorization of synthetic dyes |
|
2014 |
Microbial production of epsilon poly lysine and its specific conjugates for effective drug targeting |
|
2016 |
Evaluation of polyphenols (Taxifolin and Quercetin) for anticancer activity by in-silico and in-vitro studies |
|
2018 |
Water soluble nanoparticle preparation and characterization of lipid soluble drugs |
|
2020 |
Studies on protease inhibitor production of edible mushroom |
|
2019 |
Studies on antidiabetic potential of Viciafaba beans by in silico and in vitro approach |
|
2023 |
Microbial Production and characterization of Asparaginase. |
|
2023 |
Therapeutic potential of Gedunin and its derivative |
|
2024 |
In silico and in vitro evaluation of Daru haridra as therapeutic agent |
|
2025 |
Production and characterization of bioactive constituents of natural isolate of Streptomyces sp. |
List of Patents:
|
S. No. |
Year |
Title |
Current status |
Application No. |
|
1. |
2023 |
A METHOD OF MICROBIAL PRODUCTION OF A BIOACTIVE COMPOUND |
Published |
202411067789 |
|
2. |
2025 |
A PROCESS FOR BIOSYNTHESIS OF A BIOPOLYMER |
Filed |
202511052981 |
|
3. |
2025 |
A PROCESS FOR BIOSYNTHESIS OF A BIOPOLYMER USING LICHI AS BIOMASS |
Filed |
- |
|
4. |
2025 |
ECO-FRIENDLY SYNTHESIS OF CARBON QUANTUM DOTS FROM BIOMASS WASTE |
Filed |
- |
Recognition:
The International Young Scientist (Jan 2022): Issued by Science Father
https://www.youtube.com/watch?v=lVKerZ5y9io
Membership:
- Society for Immunotherapy of Cancer (SITC), Milwaukee, Wisconsin, USA : Life Time Member
Media Coverage:
- DD News Uttar Pradesh:
https://www.youtube.com/live/AVIlyoZ0T-c?si=5c-u6MeJlFk895i2
- The Economics Times: IIT-BHU scientists develop green hydrogen from sugarcane waste
- Hindustan: आईआईटी बीएचयू के वैज्ञानिकों ने गन्ने के बायोमास अपशिष्ट और एक नई जीवाणु प्रजाति की मदद से हरित हाइड्रोजन उत्पादन की तकनीक विकसित की
- Live VNS: IIT-BHU develops green hydrogen from sugarcane waste, discovers new technology