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Projects

The Department conducts cutting edge research on discovery and formulation development of therapeutic agents for treatment of human diseases. The thrust area(s) of the Department  includes therapeutic intervention of infectious diseases, inflammatory diseases, neurological disorders, diabetes, cancer etc.

Research is conducted across the areas of drug discovery and formulation development from lead discovery from synthetic and natural sources, lead optimization through computational approaches, biochemical and pharmacological evaluation in animal models, clinical evaluation of drug candidates and drug delivery. Advanced chemical and bio-analytical tools including HPLC, HPTLC, NMR, SEM etc are utilized to accelerate the process of lead discovery and development research.

Interdisciplinary research projects involving faculty from other relevant disciplines such as Institute of Medical Sciences and Faculty of Science of Banaras Hindu University provides an unique research environment and opportunity for the research students and faculty members.

Some of the major research projects run by the faculty members of the Department are listed below.

I. New Projects

 

S. No.

Project Title

Project Investigator(s)

Funding Agency

Amount

Duration

1

Development of Novel Ophthalmic Formulation of Dorzolamide For Continuous Treatment of Glaucoma

Dr.J.K.Pandit

UGC

Rs.10.562 lakhs

2 years
(2006-2008)

2

Ethnomedicinal plants as a source of New therapeutic agents against Psoriasis

Dr.S.K.Singh

AYUSH

Rs.18.00 lakhs

3 years
(2006-2009)

3

Upgradation of Existing Instructional Facilities

Dr.J.K.Pandit

AICTE –MODROBS

Rs.13.00 lakhs

2 Years
(2007-2009)

4

Development of Solid Lipid Nanoparticles for Controlled Release of Praziquantel, An Anthelmintic Drug

Dr.Sanjay Singh – PI & Dr.J.K.Pandit – Co-PI

UGC

Rs.9.026 lakhs

3 years
(w.e.f. 1.4.2007)

5

Development of Solid Lipid Nano-particles for Controlled Release of Zidovudine, An Anti-HIV Drug

Dr.Sanjay Singh

AICTE - RPS

Rs.19.99 lakhs

2 years
(w.e.f. 10.09.07)

6

Biochemical Evaluation of Newer Isatin Derivatives as Potential Anticonvulsants

Dr.Senthil Raja, A.

AICTE - RPS

Rs.11.41 lakhs

2 years

(w.e.f. Oct 2007)

7

Phytochemical Standardidazation and Pharmacological Evaluation of Some Potential Anti-Gastroduodenal Ulcer Plants

Mr.A.N.Sahu

AICTE - RPS

Rs.10.65 lakhs

2 years
(w.e.f. Oct 2007)

8

Nanoparticles of Dexamethazone for Delivery to Posterior Segment of the Eye

Dr.J.K.Pandit

AICTE - RPS

Rs.18.00 lakhs

2 years
(w.e.f. Jul 2008)

9

Neuropsychopharmacological studies on standardized extract of Fumaria Indica

Dr.Vikas Kumar

ICMR

Rs.8.00 Lakhs

3 years

(w.e.f. 2008)

10

University Grants Commission Assistance to the Department of Pharmaceutics, B.H.U.

Chairman: HOD

Co-ordinator: Dr. Sanjay Singh

UGC-SAP DRS Phase-I

Rs.48.00 Lakhs

5 years
(w.e.f. Apr 2009)

11

Standardization of Cryptocoryne spiralis (Retzius) Fosch. Ex Wydler and Aconitum heterophyllum Wall

Dr.S.Hemalatha & Mr.A.N.Sahu

AYUSH

Rs.16.50 lakhs

2 years

(w.e.f. Sep 2009)

12

Pharmacological Evaluation of Atypical Anti-Osychotics for Anti-Post Traumatic Stress Disorder Activity in Rodent Models

Dr.K.Sairam

CSIR-ERD

Rs.11.01 lakhs

2 years
(w.e.f. Sep 2009)

13

Adaptogenic activity of standardized extract WS@1375 developed by Dr.Willmar Schwabe GmbH & Co. KG

Dr.Vikas Kumar

 

Dr. Willmar Schwabe GmbH & Co. KG, Karlsruhe-76227, Germany

Rs.12.50 lakhs

One year
(w.e.f. Feb 2010)

14

Anxiolytic activity of Silexan and neuropharmacological characterization of WS®-1375.

Dr.Vikas Kumar

 

Dr. Willmar Schwabe GmbH & Co. KG, Karlsruhe-76227, Germany

Rs. 35.42 Lakhs

Fifteen months

(December 2011-February 2013)

15

Pharmacological Evaluation of Atypical Anti-psychotics for Anti-Post Traumatic Stress Disorder Activity in Rodent Models.

Dr. K. Sairam

CSIR, New Delhi

Rs. 19.99 Lakhs

2009-2012

16

Experimental and clinical basis of novel treatment strategy using mitochondrial modulators in neonatal anoxic injury.

Dr. K. Sairam

DBT, New Delhi

Rs. 71.99 Lakhs

2012-2015

17

Design, Synthesis and in vitro Anticancer Evaluation of Some Novel Curcumin Analogs

Dr. K. Sairam - PI
Dr. Senthil Raja A - Co PI

M/s Disto Pharmaceuticals Pvt. Ltd. Hyderabad

Rs. 6.54 Lakhs

2012-2013


 

II. Projects completed

 

S. No.

Project Title

Project Investigator

Funding Agency

Amount

Duration

1

Phytochemical work on Banana Powder

Dr.S.Ghosal 

Reckitt & Colman of (I) Ltd., Calcutta.

Rs.1.5 lakhs

2 years
(1982-83)

2

Targetting of Adriamycin Microspheres to Lung Cancer

Dr.Jagdish Singh

UGC

Rs.3.63 Lakhs

3 years
(1992-94)

3

Factors affecting the pharmacokinetics of some transdermally delivered cardioactive drugs

Dr.J.K.Pandit

ICMR

Rs.1.67 lakhs

2 years
(1993-95)

4

Chemical & Pharmacological Investigation of Some Medicinal Plants

Dr.P.V.Sharma

UGC

Rs.60,000/-

3 years
(1993-95)

5

Chemical Evaluation of Lindenbergia urticaefolia

Dr.P.V.Sharma

UGC

Rs.60,000/-

2 years
(1994-96)

6

Development of a Low Cost Pharmaceutical Device for Targetted Long Term Treatment of Periodontal Disease

Dr.J.K.Pandit

DST

Rs.3.10 lakhs

2 years

(1997-99)

7

Long Acting Topical Ocular Delivery of Anti-infective, anti-inflammatory agents via in situ forming gels and soluble inserts

Dr.J.K.Pandit

UGC

Rs.5.90 lakhs

3 Years
(1997-99)

8

Biodegradable Scleral Implant of Ganciclovir: A promising Drug Delivery System for Treatment of Cytomegalovirus Retinopathy.

Dr.J.K.Pandit

AICTE

Rs.7.00 lakhs

2 Years

(1999-2002)

9

Modernisation of Laboratories of Dept. of Pharmaceutics, IT, BHU.

HOD

AICTE

Rs.9.80 lakhs

3 years

(2000-2003)

10

Semicarbazones as Novel anti-convulsants and their Biochemical Investigation.

Dr.S.K.Patnaik

AICTE -TAPTEC

Rs.9.50 lakhs

3 Years

(2000-2003)

11

Design and Evaluation of Long Acting Cost Effective Osmotically Controlled Delivery Systems of Anti-inflammatory.

 

Dr.B.Mishra

AICTE –TAPTEC

Rs.11.95 lakhs

3 Years

(2000-2003)

12

Neuropsychopharmacological Studies on Indian Hypericum perforatum Linn.

Dr.P.N.Singh

ICMR

Rs.2.40 lakhs

2 years

(1999-2000)

13

Isolation of Marker Compounds from Medicinal Plants

Dr.S.K.Singh

DRDC,

Calcutta

Rs.0.50 lakhs

2 years
(2001-2003)

14

Isolation of Marker Compounds from Withania somnifera

Dr.S.K.Singh

Natreon Inc. India, Kolkatta

Rs.0.50 lakhs

2 years
(2004-2005)

  This page was last updated on 10 Jan 2013